Instead of amniotic fluid, tissue from the placenta is examined. Part of the placenta consists of a membrane layer called the chorion. Small hair-like projections called villi protrude from the chorion and serve to transfer nutrients, oxygen, and antibodies from you to your baby. These chorionic villi contain fetal cells complete with the baby's chromosomes and DNA.

When and how is chorionic villus analysis done?

Usually performed between the 9th and 14th weeks of pregnancy, earlier than amniocentesis. If you need a diagnostic test early in pregnancy, your doctor will recommend a villus test, since early amniocentesis can cause complications.
During this procedure, the doctor takes a sample of chorionic villus cells by inserting a thin, hollow tube through the vagina and cervix or a needle through the abdominal wall. The sample is then sent to a laboratory for analysis. Both approaches are considered equally safe. The choice depends on the position of the chorion and the experience of the doctor. It is usually easier to reach the chorion on the back of the uterus through the cervix. The chorion on the anterior side is equally accessible for both approaches.

Before the procedure, an ultrasound is performed to determine the position of the chorion; ultrasound is used throughout the procedure.

It is important that the procedure is performed by an experienced doctor, as it requires more skill than amniocentesis. The risk is about the same, slightly higher than with amniocentesis. Miscarriage, post-procedural complications, and Rh sensitization are possible.

There was some concern that this procedure increased the likelihood of limb defects. Previously, studies have shown a slight increase in abnormalities in limb development after villus sampling. However, other studies have not found this.

Impairments in the development of the limbs are only likely if the procedure is performed before the 9th week of pregnancy.

What chorionic villus sampling results can tell you

Like amniocentesis, chorionic villus sampling can show whether the baby has chromosomal abnormalities, particularly Down syndrome. In pregnancies complicated by certain genetic diseases, the DNA obtained from the test can be used to test for these diseases. Advantages over amniocentesis are that results can be obtained earlier in pregnancy.

Test accuracy and capabilities

The percentage of false positive results is less than one. A false positive result means that the test shows the presence of an abnormality, but in fact the child does not have one. If the result is negative, you can be almost certain that the baby does not have chromosomal abnormalities. But with this test it is impossible to check for all diseases. For example, it does not recognize a neural tube defect such as spina bifida.

Chorionic villus biopsy analysis is done when there is a risk of genetic or chromosomal pathology of the fetus. The essence of the method is to study microscopic particles of chorionic villi, which in their genetic structure are absolutely identical to the cells of the unborn child. The procedure was first used in 1968, and since then it has become widespread. Chorionic villus biopsy gives results already in the early stages and makes it possible to identify many hereditary diseases and chromosomal changes in cells. Complications are rare; according to various sources - from 1% to 3%. Diagnostic reliability is high; In 99% of cases, chorionic villus biopsy reveals a genetic pathology.

Indications for the use of chorionic villus sampling

Chorionic villus biopsy is an invasive technique. No matter how correctly it is carried out, there is always a risk of complications. Doctors always compare the benefits and harms of the procedure. Therefore, fetal chorionic villus biopsy is performed exclusively when indicated. Here are the main ones:

• The woman expecting a child is over 35 years old.
• If there is a child in the family with Down syndrome or other chromosomal pathologies, or they were identified in the fetus in previous unsuccessful pregnancies.
• When the family has a child with multiple pathologies of intrauterine development.
• One or two parents have hereditary diseases or may be carriers of them.
• Ultrasound or laboratory tests revealed signs of intrauterine pathology of the fetus.
• To determine the sex of a child if there is a risk of genetic pathology transmitted sexually.

After thirty-five years, the risk of chromosomal pathologies increases, therefore chorionic villus biopsy at this age is completely justified. According to statistics, for every 700 births at this age, one case of multiple pathologies of intrauterine development, or a disease associated with chromosomal changes in cells, is diagnosed. If the pathology is diagnosed by chorionic villus biopsy at an early stage, parents can decide whether to continue the pregnancy or not. Also, a chorionic villus biopsy helps clarify the diagnosis, since conventional ultrasound and biochemical tests do not provide reliable information. The technique makes it possible to identify about 3,800 different pathologies, with the exception of neural tube malformations. The timing of chorionic villus biopsy is too early to judge the pathology of the nervous system, which develops intensively at approximately the 20th week of pregnancy. Therefore, they are judged already in the second trimester, performing amniocentesis or cordocentesis.

Preparation for chorionic villus biopsy

Chorionic villus biopsy analysis is not done spontaneously; it requires certain preparation. The study is scheduled in advance and the woman is asked to do a number of preliminary studies. Here is their list:

• Tests for a number of infections (HIV, syphilis, viral hepatitis B and C, and, if indicated, for TORCH infections). The statute of limitations for analyzes should be no more than three months.
• Microscopic examination of vaginal smears.
• General blood test with leukocyte formula, no more than a month old.
• General urine examination.
• Blood test of the expectant mother for group and Rh factor.

A woman undergoes many examinations when she is registered at the antenatal clinic. So there is no need to conduct additional research. If the mother has a negative Rh factor, after a chorionic villus biopsy, anti-Rhesus immunoglobulin must be administered; you must stock up on the medicine in advance (if it is not in the clinic). For HIV-infected women, the dose of antiretroviral drugs is increased before the study. If a transcervical chorionic villus biopsy is to be performed, be sure to pay attention to a vaginal smear. If the indicators are poor, the procedure is cancelled. Before the test, the woman may be asked to fill or empty her bladder, depending on the chorionic villus sampling technique.

Chorionic villus biopsy: results and technique

Chorionic villus biopsy has strict timing. This situation is due to the fact that the thickness of the chorion for safe and reliable analysis must be at least one centimeter. This size is reached approximately 7-8 weeks after conception. But with such an early fetal chorionic villus biopsy, there is a greater risk of complications, in particular, pathology of the fetal limbs and termination of pregnancy may occur. After the thirteenth week, the placenta begins to form and chorionic villus biopsy can no longer be done. Therefore, the optimal period for the procedure is 10-12 weeks of pregnancy.

Chorionic villus biopsy has several techniques. Considering the place where the placenta develops, transabdominal (through the anterior abdominal wall) and transcervical (through the vagina and cervical canal) chorionic villus biopsy is performed. The first option is preferable; it gives fewer complications. The second option is indicated for the formation of the chorion on the posterior uterine wall, where access through the anterior abdominal wall is blocked. Also, fetal chorionic villus biopsy can be performed using a single-needle or double-needle method.

Abdominal chorionic villus sampling done using the free-hand method or using a puncture adapter. The latter method is more advanced, as it allows you to more accurately control the movement of the needle. The patient lies down on the couch, the puncture site is treated with an antiseptic, anesthesia is not given, since the puncture does not cause much pain. Fetal chorionic villus biopsy is performed under close ultrasound guidance.

With single-needle technique Chorionic villus biopsy is performed using one needle with a mandrel with a diameter of 20G. The anterior abdominal wall and the muscular layer of the uterus are pierced one by one. The needle is then directed parallel to the chorionic membrane directly into the chorionic tissue. The mandrin is removed, a syringe with five milliliters of nutrient medium is attached to the needle, and the material is taken out with a piston. For a chorionic villus biopsy analysis to be effective, you need to obtain at least 5 mcg of biopsy material. With the two-needle technique, a guide needle with a diameter of 16-18G is used, inside of which there is a biopsy needle with a diameter of 20G with a mandrel. The first needle is used to puncture tissue, the second is used directly for chorionic villus biopsy.

Transcervical biopsy fetal chorion is indicated if its membranes are located on the posterior uterine wall. The woman lies down in the gynecological chair, as during a routine examination. The vaginal walls and cervix are fixed using specially designed forceps. Then a polyethylene catheter with a flexible mandrel inside is inserted into the canal, which blocks its lumen and makes it more rigid. Under ultrasound control, the catheter is inserted between the wall of the uterus and the chorionic membranes. Then the mandrin is removed and a syringe with five milliliters of nutrient medium is attached to the proximal end of the catheter. A biopsy of the fetal chorion is performed by aspiration, taking at least 5 mg of material. The procedure is practically painless, the discomfort is comparable to that of taking a smear for research.

In case of multiple pregnancy, chorionic villus biopsy is performed using the same technique as when carrying one child. In this case, material should be taken from both chorions. This requires even more experience of the doctor and perfection of technology. When performing a chorionic villus biopsy during multiple pregnancies, it is very important to accurately determine the chorions of each embryo.

After collection, the cells are cultured in a special medium, stained, and then the material is carefully examined under a microscope using modern computer techniques. Problems in analyzing a chorionic villus biopsy can arise if there is too little material, maternal cells accidentally get into the biopsy sample, or the woman experiences “placental mosaicism” syndrome, when the chromosomes in the chorion cells differ in their composition. In such cases, chorionic villus biopsy is repeated or supplemented with other techniques at a later date. The risk of complications during the second chorionic villus sampling remains the same, and significantly increases only with the third attempt.

Chorionic villus biopsy analysis takes quite a long time, since cells with different types of mutations have different cultivation times. Results can be obtained in 10-14 days. Its reliability is almost one hundred percent (about 99% according to statistics). Obtaining results of chorionic villus biopsy in private clinics may be shorter. The fact is that many of them cultivate the material using the accelerated FISH method. It is more expensive and in some situations less accurate. To obtain more reliable results, chorionic villus biopsy analysis is performed using both methods.

Reactions and complications after chorionic villus biopsy

Fetal chorionic villus biopsy is performed on an outpatient basis and does not require hospitalization. In some cases, the woman is advised to stay in the clinic for an hour or two in order to receive timely assistance for early complications. Also, after a chorionic villus biopsy, it is advised to take sick leave, move less, and not engage in physical work. If you experience the slightest disturbance in your health or any alarming symptoms, you should return to the hospital.

Reactions after chorionic villus biopsy vary. Some of them are completely natural and pose no threat to either mother or child. Others are complications; fortunately, these are rare. Immediately after a chorionic villus biopsy, a woman may feel nagging or cramping pain of the same intensity as during menstruation. If they do not intensify, there is no bleeding, then help is not required. Approximately every third woman may experience slight bleeding after a chorionic villus biopsy using the transcervical method. With transabdominal chorionic villus biopsy, this phenomenon is rare and occurs in isolated cases.

Chorionic villus biopsy in approximately 4% of cases leads to the formation of a hematoma between the wall of the uterus and the chorionic membrane. Small hematomas resolve by approximately the 16th week of pregnancy and do not pose a threat to the development and life of the fetus. Large hemorrhages can lead to premature termination of pregnancy. The risk of miscarriage after chorionic villus sampling is 2-3%. Infectious complications when the procedure is carried out correctly occur in 0.3% of cases. But to prevent them, women are still prescribed a short course of antibiotics. A rare complication is a violation of the integrity of the membranes; its frequency does not exceed 0.3%. α-fetoprotein levels may temporarily increase, but they return to physiological values ​​around the sixteenth or eighteenth week. It is during such periods that the study of this indicator is most informative.

Chorionic villus biopsy: price

The cost of the procedure largely depends on the level of the clinic and its location. So a chorionic villus biopsy in Moscow will be more expensive than in the regions. In public medical institutions, chorionic villus biopsy may cost less than in private ones. It ranges from 6,000-7,000 thousand rubles in regular hospitals, to 18,000 - 27,000 rubles in private clinics. Chorionic villus biopsy in Moscow may vary in cost, depending on the level of equipment, the method of culturing cells, the number of pathologies diagnosed during it, the level and qualifications of doctors. In private clinics, chorionic villus biopsy and its price are also determined by the comfortable conditions of the patient’s stay. The price may also include the price of medications.

Start your path to happiness - right now!

At 12 weeks I went for genetic screening tests. The procedure is as follows: an ultrasound is performed, you donate blood for hCG and PAPP-A hormones, then the data is entered into a computer program, along with your medical history, your age, weight; the program calculates the risks.

They called on the 3rd day and said that the high risk for Down syndrome was 1:125, feelings about this were described above by other women. Although I can say that I am a fairly sensible and stress-resistant person. After crying a little, I went to the hospital. Ultrasound markers are good - pay attention to the collar space (should not be enlarged), nasal bone, blood flow in the venous passage - these are some of the most important indicators for chromosomal abnormalities. Hormones are within the physiological norm. Why was I called? The doctors were confused by the fact that my hCG was at the lower limit norm, and PAPP-A, on the contrary, was at the upper limit, and these “scissors” and plus my age of 36 years gave rise to a risk. They scheduled a biopsy for me on the day of departure; I had to fly to Prague for a week. I didn't know what to do. I remembered that my cousin wrote a dissertation on this issue; she is a doctor at a large perinatal center in St. Petersburg. I scan the results and send them to her. I bring her letter.

Tanyusha, hello!
In my opinion, you can completely trust the research results that you sent. Everything is very clear and competent.
The risk of Down's disease is not very high, in fact just under 1 in 100.
Keep in mind that the absence of ultrasound markers is a very important, but not an absolute criterion for the absence of chromosomal diseases.
Considering that placentobiopsy is expected, it will be possible to exclude many chromosomal abnormalities, since cytogeneticists will look at direct preparations and analyze all chromosomes (their number and structure). By the way, if you have Rh-negative blood, you can also determine the Rh-ness of the fetus (this is a molecular genetic study).The procedure is absolutely safe, and your peace of mind and confidence during pregnancy are very important.

At the same time, if your inner voice says that everything is okay, I think you can trust it. No one has yet canceled women's intuition :)

To summarize...
The risk of placentobiopsy is practically zero.
The information obtained as a result of the study will allow you not to worry about chromosomal diseases at all.

Consult with your husband and make a decision. Moreover, you still have time to think (you don’t need to do the procedure before the trip, that’s for sure).

And, probably, the most important and personal. Can the research result change anything? Everyone has their own answer to this question.

Listen with your heart and mind.

I consulted with my gynecologist; she also advised me to do a biopsy.

I arrived from a business trip, in one day I did all the tests necessary for a biopsy (general blood and urine test, HIV, syphilis, vaginal smear for cleanliness, Rh factor of the blood), took slippers, a robe and went to the hospital. I was determined because I didn’t want to suffer through the entire pregnancy from the unknown later. I can say that this is my first pregnancy and the child would have stayed with me in any case.

The procedure takes 3-5 minutes, it doesn’t hurt, it’s a little unpleasant, if you don’t bring yourself to a nervous breakdown, then there will be no consequences at all—even your blood pressure won’t jump. Since I am alone, I don’t have a husband. and all my relatives live far away, I am completely alone in my pregnancy. They can only support me from afar, by phone. I can say that I was the calmest in line for the biopsy, which is why it went better than anyone else.

A week later I received the result - everything is fine with the baby! No chromosomal abnormalities were found. And now a summary and small recommendations.

1. Before donating blood, go on a diet for a week - steamed food, soups, cereals, good water, nothing fatty, salty, allergenic, chocolates and other things - then eat - since all this unhealthy food can affect hormones - after all, these are protein structures .

2. For a week, no nervous hysterics, fits, nerves and tears, generally behave like an elephant - nothing should worry you, this also affects hormones.

3. During all procedures, behave calmly, treat them like any other necessary test, for example, imagine that you are taking a urine test.

4. Get tests done in competent clinics and medical centers, where these tests are performed constantly and for more than 3 years. To get reliable results.

5. Do not retake the tests if something is wrong - you will only confuse all the cards and lose money and precious time, since the most reliable results are obtained from 12 to 14 weeks.

6. Remember that many women over 35 are at risk, according to the computer program. this is an inevitable evil, take it philosophically, be prepared for it.7. You have been called to see a geneticist and he recommends a biopsy. You were prescribed a chorionic villus biopsy, or in my case, placentocentesis, as I did already at the beginning of the 15th week.

8. Find out how experienced the team will be doing this procedure for you; you can ask this at an appointment with a geneticist. I had it done at the Republican Clinical Hospital of the Republic of Tatarstan, the team has been doing the procedure for 8 years and there has not been a single case of infection or miscarriage there. The competence of specialists is questionable - look for those you have no doubt about - this is an important point.

9. Collect all the necessary tests for the procedure - some are already in your maternal passport if you registered early. Give yourself a couple of days to rest after running around hospitals - you will be assigned a day for the procedure.

10. Under no circumstances do a biopsy if you need to go somewhere, as in my case. After this procedure, you cannot bend down, wash floors, lift weights, have sex, squat sharply, go to the bathhouse, sauna, or steam your legs for 3-5 days.

11. Carry a backpack with you in case your stomach hurts.

12. During the procedure, behave calmly, control yourself, do not become limp, do not stress yourself out, do not cry or be afraid. Act like a calm, professional mom.

13. After the biopsy procedure, do not run from the hospital like someone shot, sit for at least half an hour, rest, and come to your senses. Have your blood pressure measured.

14. It is better to spend the rest of the day at home, observing bed rest.

15. Monitor your health closely for 5 days.

16. Practice has shown that bad results are reported quickly, so if they don’t call you from the hospital for a long time, don’t cry or panic, wait patiently.

17. Do not refuse the procedure because of your fears, advice from girlfriends, or Internet articles. It is better to consult a competent specialist or your gynecologist. If you were not at risk of miscarriage before the biopsy, you will not be at risk after. If there is a risk, behave more carefully.

OK it's all over Now. Good luck to all. Take care of yourself and your baby! Kiss. I love.

Chorionic villus biopsy is a special medical test performed between the tenth and twelfth weeks of pregnancy (the exact period of the “interesting position” is determined by ultrasound). With its help, you can find out the most complete information about the state of the embryo at the moment.

Procedure Fetal Condition Analysis
pregnant woman discomfort on the monitor
new life baby pregnancy

Approximately by the 16th week of the “interesting position,” the chorion is completely transformed into the placenta. But even before the 19th week, you can do a chorionic villus biopsy of the tissues that are needed for the study (it happens that for certain reasons the test was not carried out at the ideal time). But the material will be taken from the placenta, and not from the chorion.

During a biopsy, cells located in the outer membrane of the fetus, adjacent directly to the uterus, are selected. This membrane is entirely covered with villi and is called chorion.

One of the significant disadvantages of the procedure is the price of this procedure. But, as they say, this is not the time to save money.

Determination of fetal health status

Why this procedure is necessary:

• to find out whether the growing embryo has any abnormalities or whether there is any cause for concern;
• Using this procedure, many diseases are diagnosed, including hereditary ones (for example, hemophilia);
• analysis of chorionic villus biopsy with a very high, almost 100% probability allows you to identify various defects in the fetus that arise due to chromosomal abnormalities (the most famous and common such defect is Down syndrome);
• Based on the test results, the woman has time to weigh the pros and cons and make a final decision: to continue her pregnancy or not (if she learns about possible risks and abnormalities of the embryo).

Indications for use

Indications for the procedure are as follows.

1. Chorionic villus sampling is highly recommended for pregnant women who have already celebrated their 35th birthday. This is due to the fact that there is a direct relationship between the frequency of congenital defects and the woman’s age. The older the expectant mother, the correspondingly higher the risk.
2. The woman already had a pregnancy, which resulted in a child with congenital defects.
3. The expectant mother has ever previously had a spontaneous miscarriage or a stillbirth.
4. The medical record indicates that the expectant mother has ever complained of a prolonged absence of menstruation (more than 6 months a year).
5. The results of the first ultrasound, mandatory for all expectant mothers, which is carried out from the 12th to the 14th week of pregnancy, showed that the fetus is predisposed to developmental abnormalities.
6. The parents were unable to conceive a child on their own for a long time, as a result of which they were diagnosed with primary infertility.
7. The parents are blood relatives (the risk of pathologies in the fetus is high, a chorionic villus biopsy is required).
8. One or both parents have a genetic disorder. The test will determine whether these disorders are passed on to the fetus.
9. It is necessary to determine the sex of the unborn baby (some genetic diseases are typical only for boys, for example, hemophilia of any type).
10. Unaware of the pregnancy, the woman took an x-ray.
11. At an early stage of the “interesting situation,” the woman took medications that had a negative effect on the nascent life. In this case, a chorionic villus sampling performed at 10, 11 or 12 weeks usually shows that the risk of birth defects in the fetus is extremely high.
12. At the time when conception had already occurred, the expectant mother was affected by unfavorable factors. For example, she could have been in an area with a high radioactive background or inhaled harmful substances.

Methods for performing the procedure

How a chorionic villus biopsy is performed during pregnancy, see photos and descriptions below.

There are different reviews about chorionic villus biopsy. The overwhelming majority of women note that this procedure is painless, although not pleasant: both physically and psychologically.

Mostly those who had it done on time, but the results were not confirmed or were not reliable enough, speak negatively about chorionic villus biopsy. This is extremely rare, but it happens, because the achievements of modern medicine are not 100% perfect.

Medical personnel usually report the results of a chorionic villus biopsy with an identified risk of Down syndrome in the fetus as quickly as possible, literally as soon as they become known. Conversely, the absence of news in this case is good news.

Risks and possible dangers

A test to identify possible developmental anomalies in the fetus is, of course, an important procedure, but, unfortunately, it is not absolutely safe for both the fetus and the pregnant woman herself. After a chorionic villus biopsy, complications for the expectant mother and/or the pregnant fetus are possible.

Analysis for the presence of pathologies

Risk for the expectant mother: during the test, an infection may enter the uterine cavity.

Risks to the fetus:

• threat of miscarriage caused by detachment of the ovum;
• the child may be born with low body weight (up to 2.5 kg);
• the baby may be born ahead of schedule.

The above risks are practically reduced to zero if the procedure is carried out by a highly qualified and experienced specialist.

Many women wonder: should they do a chorionic villus biopsy or amniocentesis, in which amniotic fluid is taken for analysis? It is worth noting that the danger to the mother and embryo in both cases will be approximately the same. The reliability of both tests is also no different.

However, amniocentesis is performed at a different time: from the 15th to the 20th week of the “interesting situation” (biopsy from the 10th to 12th week). If a decision is made to terminate the pregnancy, then at 20-22 weeks the risk of possible complications from an abortion for a woman is lower, which is a definite plus for choosing a biopsy.

It is not recommended to do a transcervical chorionic villus biopsy in the presence of one or more deciduidal polyps; it is also not worth removing polyps - this poses a risk of miscarriage and can also cause premature birth.

Contraindications for the procedure are also:

• risk of miscarriage;
• inflammatory diseases of the female organs or abdominal skin (depending on the type of biopsy performed);
• HIV infection of an expectant mother is not a reason to refuse the test, but since the likelihood of transmission of infection from mother to fetus increases, the woman is prescribed an increased dose of antiretroviral drugs.

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Chorionic villus biopsy (CHB) is a modern invasive method of prenatal diagnosis, which makes it possible to accurately diagnose chromosomal diseases, gene diseases, and intrauterine infections. This research method has become very widespread and is successfully used throughout the world. You can also undergo the chorionic villus biopsy procedure at Mother and Child.

What is chorionic villus sampling?

Diagnosis of genetic diseases is possible by examining cells from chorionic villi. Chorionic villus biopsy is a puncture of chorionic tissue for subsequent study. As a rule, this procedure is performed under ultrasound guidance without anesthesia through the anterior abdominal wall at 10-12 weeks of pregnancy.

Before carrying out this procedure, it is necessary to conduct an ultrasound to determine the exact duration of pregnancy, assess the cardiac activity of the fetus, the number of fetuses, the tone of the uterus, and the location of the placenta.

Then the anterior abdominal wall of the pregnant woman is treated with an antiseptic and a needle is inserted through it directly into the uterus, where a small amount of chorionic villi is aspirated.

After the procedure, women with a negative Rh factor are given the required dose of immunoglobulin to avoid sensitization.

How dangerous is this procedure?

Chorionic villus biopsy is an invasive diagnostic method with a very high degree of safety. However, there is still a small chance of complications. The risk of miscarriage due to this procedure in our clinics does not exceed 1%.

Indications for chorionic villus biopsy?

Direct indications for chorionic villus biopsy are the following factors:

• high risk of chromosomal abnormalities based on biochemical screening or non-invasive test results;
• in previous pregnancies there were chromosomal abnormalities in the fetus;
• ultrasound examination showed signs of various fetal development disorders;
• there are genetic diseases in the family that are inherited;
• carriage of chromosomal rearrangements by one of the spouses.

Are there any contraindications for this study?

There are no absolute contraindications to invasive methods of research and chorionic villus biopsy. Relative ones include:

• the presence of an acute inflammatory process;
• exacerbation of chronic diseases;
• pronounced hypertonicity of the uterus;
• bleeding from the cervix.

How long should I wait for results?

A standard cytogenetic study does not require the cultivation of chorionic cells, so you will receive a conclusion about the karyotype of the fetus in 2 days.

It is also possible to conduct an extended analysis (molecular genetic test) of chromosome microrearrangements (microdeletions and microduplications) from the sample obtained during chorion biopsy, which will eliminate more than 400 severe genetic syndromes that are not detected by standard karyotyping. Indications for a molecular genetic test are malformations or ultrasound markers of fetal pathology, such as expansion of the thickness of the nuchal translucency, fetal growth retardation, size dissociation, etc. This analysis requires 10-12 days.

How to do a chorionic villus biopsy?

If there are indications for this procedure, a chorionic villus biopsy can be done at Mother and Child in a one-day hospital. The advantage of our clinics is the high qualifications of all the specialists working in them and the availability of the most modern equipment. Here you will get the most accurate results, and the procedure itself will be carried out with maximum comfort.